HERE is a summary of some recent studies on COVID-19. They include research that warrants further study to corroborate the findings and that have yet to be certified by peer review.
Researchers working toward one vaccine for many variants
Two separate research teams last week reported on laboratory tests of monoclonal antibodies that appear to protect against a broad range of COVID-19 virus variants. One study, published on Wednesday in The New England Journal of Medicine, identified "high-level, broad-spectrum" antibodies in blood samples from survivors of the original SARS outbreak in 2003 who recently received the Pfizer/BioNTech vaccine against SARS-CoV-2, the virus that causes COVID-19.
In test tube experiments, some of the SARS survivors' antibodies induced by the vaccine could neutralize not only all of the current SARS-CoV-2 variants of concern, but also five viruses that have been identified in bats and pangolins and that have the potential to cause human infection.
In a separate study, published on Thursday in the journal Immunity, another research team describes an antibody that was highly protective at low doses against a wide range of COVID-19-causing variants in mice.
"The antibody attaches to a part of the virus that differs little across the variants, meaning that it is unlikely for resistance to arise at this spot," the authors said. The findings from these studies could be a step toward developing new antibodies that would be effective against multiple different coronaviruses, the two teams say.
Infectious virus shedding may be lower in breakthrough cases
Vaccinated people who get infected with COVID-19 have high levels of the virus in their noses and throats but not all of that virus is infectious, a new study suggests. Among 24,706 vaccinated healthcare workers in The Netherlands, 161 developed mild or asymptomatic breakthrough infections, mostly due to the Delta variant of the coronavirus.
The viral levels on nose-and-throat swab samples from these patients were just as high as in unvaccinated healthcare workers who were infected last year with the original strain of the virus. But in test tube experiments, the virus from vaccinated patients was less efficient at reproducing itself than virus from unvaccinated patients, probably because some of it had been neutralized by antibodies from the vaccine, the researchers speculate.
In a report posted on medRxiv on Saturday ahead of peer review, they conclude that shedding of infectious virus is reduced in breakthrough cases, although patients are still contagious.
Antibodies fade faster after vaccine vs actual infection
Protective antibody levels decline faster in recipients of the mRNA COVID-19 vaccine from Pfizer/BioNTech than in COVID-19 survivors, according to doctors at one of Israel's largest HMOs. They tracked antibody levels in 2,653 adults who received two doses of the vaccine and in 4,361 COVID-19 survivors who were never vaccinated.
Antibody levels fell by up to 40% per month in vaccinated participants, versus less than 5% per month in so-called convalescents. After six months, about 84% of vaccine recipients still had detectable antibodies, whereas roughly 90% of convalescents still had detectable antibodies after nine months.
Dr. Ariel Israel of Leumit Health Services, coauthor of a reported posted on Sunday on medRxiv ahead of peer review, noted that antibodies are not the immune system's only weapon against the virus.
Still, he said, the data suggests that antibody protection in Pfizer vaccine recipients wanes at a higher rate than in COVID-19 survivors. Leumit researchers had previously reported that breakthrough infection rates increase starting about five months after vaccination.
Dr. Israel said the combined data argues for a booster shot five months after the second injection, especially for high-risk individuals.
Reuters
Tue Aug 24 2021
![Researchers seek powerful antibody against many variants; breakthrough cases may be less infectious Researchers seek powerful antibody against many variants; breakthrough cases may be less infectious](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2021-08/61629770719_MASKS.jpg)
The summary includes research that warrants further study to corroborate the findings and that have yet to be certified by peer review. -REUTERS
![PRK Nenggiri: PN ada peluang menang, tapi jangan over-confident - Muhyiddin PRK Nenggiri: PN ada peluang menang, tapi jangan over-confident - Muhyiddin](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-04/51713678198_MuhyiddinYassin.jpg)
PRK Nenggiri: "PN ada peluang menang, tapi jangan over-confident" - Muhyiddin
Muhyiddin optimis dengan kemenangan calon PN, Mohd Rizwadi Ismail sekali gus mempertahankan kerusi DUN Nenggiri.
![Ahli ekonomi yakin pertumbuhan KDNK sekitar 5.8 peratus pada suku kedua 2024 Ahli ekonomi yakin pertumbuhan KDNK sekitar 5.8 peratus pada suku kedua 2024](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-06/81717305735_EkonomiMalaysia.jpg)
Ahli ekonomi yakin pertumbuhan KDNK sekitar 5.8 peratus pada suku kedua 2024
Kalangan ahli ekonomi yakin KDNK Malaysia bagi suku kedua 2024 akan berkembang pada 5.8 peratus berbanding 4.2 peratus pada suku pertama tahun ini.
AWANI Pagi: Berita tumpuan & menarik di astroawani.com [15 Ogos 2024]
Antara fokus AWANI Pagi bersama Nursyazwani Saiful Sham dan Afiezy Azaman
- Mayat lelaki di jambatan Klang dipercayai YouTuber Nidza Afham
- BNM denda Maybank, CIMB kerana gangguan perkhidmatan berpanjangan
- JIWA SME: Inovasi kuih sejuk beku jadi kudapan jemaah tunai umrah
#AWANInews #AWANIpagi
- Mayat lelaki di jambatan Klang dipercayai YouTuber Nidza Afham
- BNM denda Maybank, CIMB kerana gangguan perkhidmatan berpanjangan
- JIWA SME: Inovasi kuih sejuk beku jadi kudapan jemaah tunai umrah
#AWANInews #AWANIpagi
![Cisco akan kurangkan 7 peratus tenaga kerja globalnya Cisco akan kurangkan 7 peratus tenaga kerja globalnya](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-08/41723681507_Ciscologo.jpg)
Cisco akan kurangkan 7 peratus tenaga kerja globalnya
Langkah mengurangkan kakitangan itu dijangka melibatkan kos pra-cukai sehingga AS$1 bilion.
Jiwa SME: Kuih tradisonal sejuk beku 'diterbangkan' ke Tanah Suci
Inovasi pembuatan makanan sejuk beku, terutama kuih muih tradisional telah berjaya membawa produk itu ke peringkat global, terutama dalam memenuhi citarasa jemaah haji dan umrah rakyat Malaysia di Tanah Suci Mekah dan Madinah.
![Gol sulung Mbappe bantu Real Madrid juarai Piala Super UEFA Gol sulung Mbappe bantu Real Madrid juarai Piala Super UEFA](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-08/51723679998_KylianMbappe.jpg)
Gol sulung Mbappe bantu Real Madrid juarai Piala Super UEFA
"Ia adalah malam yang hebat. Ia adalah detik yang hebat untuk saya. Dan kami memenangi kejuaraan, yang penting - di Madrid anda perlu sentiasa menang."
![“I love you Am, bahagialah di syurga firdausi” - Aufahanie “I love you Am, bahagialah di syurga firdausi” - Aufahanie](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-08/51723679258_AufahanieNidzaAfh.jpg)
“I love you Am, bahagialah di syurga firdausi” - Aufahanie
Air mata Aufahanie sudah kering meratapi pemergian abang tercinta, Nidza Afham yang ditemui meninggal dunia selepas dilaporkan hilang.
Konsert jelajah: Taylor Swift teruskan konsert London selepas ancaman keganasan
Taylor Swift akan meneruskan persembahan di London pada Khamis, meneruskan jelajah konsert terbesar dunia di tengah-tengah kebimbangan keselamatan susulan cubaan serangan Daesh memaksa pembatalan tarikh konsert di Vienna, minggu lalu.
Taliban rai ulang tahun ketiga pemerintahan Afghanistan
Kerajaan Taliban semalam meraikan ulang tahun ketiga pemerintahannya di Afghanistan dengan perarakan tentera yang memberi penghormatan kepada bom buatan sendiri yang digunakan ketika peperangan, pesawat pejuang dan perbarisan pasukan keselamatan.
![Bapa bintang bola sepak Sepanyol, Lamine Yamal ditikam - Laporan Bapa bintang bola sepak Sepanyol, Lamine Yamal ditikam - Laporan](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-08/61723677980_MounirNasraoui.jpg)
Bapa bintang bola sepak Sepanyol, Lamine Yamal ditikam - Laporan
Mounir Nasraoui, bapa kepada Lamine Yamal, ditikam pada lewat Rabu di tempat letak kereta di bandar Mataro di timur laut Sepanyol.
![Berita antarabangsa pilihan sepanjang hari ini Berita antarabangsa pilihan sepanjang hari ini](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-03/71709993909_TBBERITAx.jpg)
Berita antarabangsa pilihan sepanjang hari ini
Antara pelbagai berita luar negara yang disiarkan di Astro AWANI, berikut adalah antara yang paling menjadi tumpuan sepanjang hari ini.
![Tahap pengurusan rantaian bekalan akan dipertingkat - PM Anwar Tahap pengurusan rantaian bekalan akan dipertingkat - PM Anwar](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-08/71723553013_TBAnwarIbrahim.jpg)
Tahap pengurusan rantaian bekalan akan dipertingkat - PM Anwar
Mesyuarat MPN Ke-6 Tahun 2024 hari ini bersetuju dengan beberapa langkah bagi meningkatkan tahap pengurusan rantaian bekalan yang kukuh, berdaya tahan dan responsif kepada gangguan.
![Olimpik Paris: Lyles raih gangsa acara 200m lelaki, meskipun positif COVID-19 Olimpik Paris: Lyles raih gangsa acara 200m lelaki, meskipun positif COVID-19](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-08/81723164238_NoahLyles.jpg)
Olimpik Paris: Lyles raih gangsa acara 200m lelaki, meskipun positif COVID-19
Lyles terpaksa berpuas hati dengan pingat gangsa dalam acara 200m, dengan emas menjadi milik atlet Botswana, Letsile Tebogo.
![[KOLUMNIS] Bahaya maklumat salah: Ancaman keamanan dan keharmonian di Malaysia [KOLUMNIS] Bahaya maklumat salah: Ancaman keamanan dan keharmonian di Malaysia](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2021-05/41622415528_fake.jpg)
[KOLUMNIS] Bahaya maklumat salah: Ancaman keamanan dan keharmonian di Malaysia
Maklumat yang salah bukan sahaja ancaman di negara-negara Barat tetapi juga semakin menjadi masalah besar di Malaysia.
![KKM belanja RM137 juta setahun bagi menyelenggara 201 klinik kesihatan KKM belanja RM137 juta setahun bagi menyelenggara 201 klinik kesihatan](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-07/71721221006_DzulkeflyAhmad.jpg)
KKM belanja RM137 juta setahun bagi menyelenggara 201 klinik kesihatan
KKM membelanjakan sebanyak RM137 juta setahun bagi menyelenggara 201 buah klinik kesihatan di seluruh negara di bawah PSK dengan kontrak selama 5 tahun bermula tahun 2022.
![Olimpik Paris 2024: Atlet renang Australia tarik diri selepas positif COVID-19 Olimpik Paris 2024: Atlet renang Australia tarik diri selepas positif COVID-19](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-07/71722334055_LaniPallister.jpg)
Olimpik Paris 2024: Atlet renang Australia tarik diri selepas positif COVID-19
Atlet renang Australia Lani Pallister terpaksa menarik diri dari acara bebas 1,500 meter selepas positif COVID-19, menurut pasukan negara itu pada Selasa.
![Biden kembali ke Rumah Putih selepas beberapa hari pengasingan COVID-19 Biden kembali ke Rumah Putih selepas beberapa hari pengasingan COVID-19](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2023-10/71696492107_JoeBiden.jpg)
Biden kembali ke Rumah Putih selepas beberapa hari pengasingan COVID-19
Presiden Amerika Syarikat (AS) Joe Biden tiba semula di Rumah Putih pada Selasa selepas beberapa hari diasingkan akibat COVID-19 dan di tengah-tengah khabar angin mengenai kesihatannya.
![Gantung Parlimen: 2 wakil rakyat dibenar mulakan semakan kehakiman Gantung Parlimen: 2 wakil rakyat dibenar mulakan semakan kehakiman](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-07/51721817034_MuhyiddinYassin.jpg)
Gantung Parlimen: 2 wakil rakyat dibenar mulakan semakan kehakiman
Mahkamah Persekutuan membenarkan dua wakil rakyat memulakan semakan kehakiman bagi mencabar nasihat Muhyiddin untuk menggantung Parlimen sepanjang tempoh darurat pandemik COVID-19.
![Biden pulih daripada gejala COVID-19, ujian negatif Biden pulih daripada gejala COVID-19, ujian negatif](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-07/71721785411_JoeBidenAirForce.jpg)
Biden pulih daripada gejala COVID-19, ujian negatif
Ujian antigen pantas BINAX adalah negatif, bagaimanapun, beliau akan terus dipantau untuk sebarang penyakit berulang.
![Biden alami gejala COVID-19 ringan, ambil ubat antiviral Biden alami gejala COVID-19 ringan, ambil ubat antiviral](https://resizer-awani.eco.astro.com.my/tr:w-177,h-100,q-100,f-auto/https://img.astroawani.com/2024-05/71716240052_TBJoeBiden.jpg)
Biden alami gejala COVID-19 ringan, ambil ubat antiviral
Kevin O'Connor berkata gejala yang dialami presiden itu mempengaruhi sistem pernafasannya.